New RNA Centre of Excellence and Training Academy to become beacon for RNA R&D

CPI, a deep-tech innovation centre, has launched an RNA Centre of Excellence and training academy to support the development, scale-up and manufacture of new and novel RNA therapies and vaccines. 

The use of RNA in oncology, and as a potential vaccine platform, has shown promise for many years, both via short chain oligonucleotides and longer chain mRNA and self-amplifying RNA. Thanks to the funding, development, clinical trials, and approval of highly effective mRNA vaccines during the COVID-19 pandemic, RNA has been demonstrated as a viable therapeutic platform and has quickly advanced our knowledge of the technology and its manufacture. 

To prepare for global demand for this exciting emerging technology, CPI is expanding capacity at its site in Darlington to include GMP facilities for the clinical manufacture of RNA, and is collaborating with the National Horizons Centre, part of Teesside University, to form a new National Training Academy for RNA Therapeutics and Vaccines Manufacture. 

CPI has extensive experience in lipid nanoparticle technology and state-of-the-art equipment to synthesise, purify, manufacture, and encapsulate mRNA and saRNA using lipid nanoparticle technology. Using biologics and formulation capabilities, CPI has developed steps to enable scale-up to 4L synthesis of a saRNA and lipid nanoparticle encapsulation process – achieving the largest scale RNA vaccine manufacture in the UK

CPI is currently the only company based in the UK capable of developing, manufacturing and encapsulating RNA vaccines ready for use in clinical trials in one location. This end-to-end capability on one site in the UK will help to drive the productivity and efficiency of RNA manufacturing. 

Read this article in full on the CPI website. 

CPI Scientist in Biologics lab

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