County Durham biosciences firm receives £250k funding to grow facilities

County Durham biosciences firm receives £250k funding to grow facilities

A North East biosciences firm has announced that it has received £250k in funding to help grow its workforce and facilities.

Magnitude Biosciences, a specialist contract research organisation based at NETPark, County Durham, received funding from the government’s Coronavirus Future Fund.

Current investors in Magnitude Biosciences, Saker Capital and North East Innovation Fund run by Northstar Ventures Capital, have matched the government funds, bringing the total to £250k.

Source: Bdaily

Chief Executive Officer at Magnitude Biosciences David Weinkove.

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The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

Durham robotics firm receives six figure funding to protect jobs past pandemic

Durham robotics firm receives six figure funding to protect jobs past pandemic

A Durham robotics company has announced that it has received six figures of funding to protect jobs and support cash flow.

Wootzano, which makes ‘electronic skin’ for robots, has received the funding package from HSBC UK through the Coronavirus Business Interruption Loan Scheme (CBILS).

The loan has enabled the company to protect multiple jobs, support cash flow and continue manufacturing during the coronavirus crisis.

With the funding in place, Wootzano is now planning for an increase in production and revenue as the business grows.

Source: Bdaily

Durham robotics firm receives six figure funding to protect jobs past pandemic

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

CPI receives three awards from the North East Process Industry Cluster

CPI receives three awards from the North East Process Industry Cluster

CPI has been announced as the winner of three awards at the annual North East Process Industry Cluster (NEPIC) award ceremony including the Young Achiever award, the Apprentice of the Year award and the Apprenticeship Employer award. The awards demonstrate CPI’s commitment to upskilling current employees and nurturing future talent.

The Apprenticeship Employer of the Year award celebrates employers with the strongest apprenticeship programmes in the region. With 15 apprentices currently working across CPI’s business units, the company is renowned for employing young talent and accelerating their professional development. The award came with a £2,000 prize that CPI has chosen to donate to Thornaby Academy, Teesside.

The Apprentice of the Year award was won by Ben Gay, who is undergoing a Laboratory Scientist apprenticeship at CPI’s National Biologics Manufacturing Centre, while completing a degree in Biological Sciences at Teesside University. His work involves ensuring smooth technical delivery and compliance with CPI’s quality procedures, as well as supporting the technical team to set up and carry out experiments.

On receiving the award, Ben said, “I am very proud to win this prestigious award. I feel privileged that CPI has offered me this platform to develop my skills and experience in the workplace. I look forward to furthering my career at CPI after I complete my degree.”

The Young Achiever award was won by Dan Wallis, who has worked at CPI for just over seven years, recently being appointed as plant supervisor. Dan was a key player in commissioning the Calysta bespoke demonstration plant under strict deadlines, and has shown remarkable professionalism and leadership in his role.

Dan Wallis said, “My position at CPI has enabled me to gain vital skills in leadership and process operations efficiencies, ensuring we offer the best possible resources to our customers who represent the sustainable future of the chemical industry.”

The awards event is organised by NEPIC and sponsored by leading names in the sector, including FujiFilm, Diosynth Biotechnologies and PX Limited. This year the event was held at Hardwick Hall, Sedgefield, and was attended by 450 people. Steve Walls presented the awards evening.

Jodie Coe, Director of Organisation Development at CPI said “The three NEPIC awards won by CPI is fantastic recognition for many years hard work and commitment to develop and inspire the young people of the North East as well as the fantastic skills of the young people in our workforce and in our apprenticeship programmes. We are very proud of Dan and Ben for their achievements as well as the wider Biotechnology, Biologics and HR team that bring the apprenticeship programme together. We will continue to have a strong focus on the development of local young scientists and engineers and connect the dots between education, meaningful experience and growing a career industry

CPI receives three awards from the North East Process Industry Cluster

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

North East based CPI announces project with GSK and AstraZeneca to accelerate optimisation of oral solid drug formulations

North East based CPI announces project with GSK and AstraZeneca to accelerate optimisation of oral solid drug formulations

CPI and the University of Strathclyde, in strategic partnership with GSK and AstraZeneca, have announced that work has begun on Grand Challenge 1, a project to develop an innovative continuous direct compression (CDC) platform at the new Medicines Manufacturing Innovation Centre.  The platform will enable oral solid dosage medicines to be formulated more robustly and efficiently.

CDC is a continuous manufacturing process that allows much greater process control than traditional batch-type pharmaceutical manufacturing methods, enabling rapid production of formulations at a range of scales. In addition, CDC offers shorter optimisation times than batch-type processes and therefore more efficient use of starting materials. The aim of Grand Challenge 1 is to further build on this process efficiency by developing a digitally-twinned CDC platform and workflow, allowing scientists to understand and optimise their formulation process in digital space. This will reduce the amount of starting materials needed for optimisation and reduce the overall cost of the technology for the end-user.

The first stage of the project is to create a flexible plug-and-play development platform. This will involve adapting and improving existing CDC models, which are often inflexible and specific for individual equipment manufacturers. Novel process analytical technology (PAT) will also be integrated into this platform.

Professor Alastair Florence, University of Strathclyde said: “The key innovation of a digital twin for the direct compression platform will radically cut down the amount of material needed to optimise formulations. It will allow companies to model their processes in digital space, providing a much deeper understanding of how APIs and excipients will perform, leading to a reduction in development times.”

The project is receiving funding from UKRI, Scottish Enterprise and the consortium’s industry partners, and is split into two phases. The development phase of the project is already underway at CMAC – the future manufacturing research hub within the University of Strathclyde.  The aim is to have a development platform operational by Q3 2020. Following this initial phase, project work will be transferred to the MMIC in Glasgow upon the centre’s completion in 2021.

Funded by UK Research and Innovation and Scottish Enterprise, the MMIC aims to ensure that the UK is a technological and innovation leader in pharmaceutical and fine chemical manufacturing, addressing some of the key challenges facing the industry. The facility will focus on the development of improved manufacturing processes, enabling a more agile, responsive medicines supply chain. The GMP-capable environment will enable new and disruptive technologies to be proven at scale, allowing the rapid adoption of next-generation processes that reduce risk, cut costs and save time.

Dave Tudor, Managing Director of the Medicines Manufacturing Innovation Centre at CPI said: “The strength of the open collaboration between CPI, GSK, AstraZeneca and University of Strathclyde cannot be overstated; we are happy to be providing our strategic and technical support. The flexible platform developed at the centre through Grand Challenge 1 will be a national asset, helping pharmaceutical companies to develop formulations faster and at reduced cost.”

North East based CPI announces project with GSK and AstraZeneca to accelerate optimisation of oral solid drug formulations

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

CPI celebrates 15 years of innovation in the North East

CPI celebrates 15 years of innovation in the North East

CPI, an independent technology innovation centre based in the North East, is celebrating 15 years of innovation across a range of different markets including pharmaceuticals, agritech, FMCG, automotive, energy and aerospace.

Initially created as one of five world-class centres of excellence tasked with delivering the North East Strategy for Success, CPI has grown significantly over the past 15 years to now employ more than 400 staff in the North East of England. Since being established in 2004 as a way to build on the existing capabilities in the North East and ensure the region remained competitive in the global marketplace, CPI has grown exponentially and has now delivered over 1700 public and private R&D projects with a value of around £500m. In turn, this has contributed to the productivity of a number of industries and has supported the development of next-generation manufacturing, highly skilled jobs and economic growth across the whole of the UK.

Since its inception, CPI has assisted over 1200 organisations, ranging from big pharma and multinational manufacturing organisations to start-ups and SMEs, and has established £123m of facilities in the North East to support companies across the UK. These include the National Biologics Manufacturing Centre, the National Healthcare Photonics Centre, the National Formulation Centre, the National Industrial Biotechnology Facility, and the National Printable Electronics Centre.

The support provided by CPI includes flexible access to a range of advanced and industry-relevant facilities for R&D, process development and scale-up work. Over the years, companies that have worked with CPI have gone on to secure over £750m of private investment either during or after the completion of these projects. Of these projects, 66% included a North East partner. Examples of projects CPI has collaborated on include helping to build the world’s largest radio telescope and facilitating the manufacture of nanoparticles to revolutionise the treatment of diabetes.

In 2011, CPI also became one of the founding members of the High Value Manufacturing Catapult, an initiative aimed at catalysing the future growth and success of UK manufacturing. This model has been applied to form other catapults across a range of industries and markets, positioning the UK as a highly competitive nation as a result.

Nigel Perry MBE FREng FRSC, Chief Executive Officer, CPI said, “Every stakeholder has contributed to the success of CPI over the last 15 years. We learn so much from both our big and small customers, and in doing so we build a capability which is of a greater value. Our staff are also brilliant, they address each new challenge with a level of innovation, inventiveness, enthusiasm, competence and capability. CPI is where it is today because of the desire of the people involved to make it a success.

In the next 15 years we will continue to develop and grow, bringing the benefit of university research to the UK. We will have a strong presence across the UK and will continue to deliver major impact for UK PLC. In particular, our aim is to deliver impact in the North East and to showcase both CPI and the further catapult network as an integral part of the success of the UK.”

NETPark is home to three National Innovation Centres

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

CPI accelerate commercialisation of lightweight products

CPI accelerate commercialisation of lightweight products

CPI is contributing its state-of-the-art facilities and capabilities to a Horizon 2020 project focused on creating an open-innovation test bed for the development and production of lightweight embedded electronics.

The ‘LEE-BED’ project will run for four years with a consortium funding value of over €10 million. The aim is to de-risk and accelerate the development and manufacture of nanomaterials and lightweight embedded electronics, giving European industry a global competitive advantage as well as creating more jobs in the sector.

Digitisation of the development and manufacturing of functional nanomaterials and printed components is essential to ensure that Europe can compete with markets in the US and Asia. By overcoming challenges such as high costs and limited volume production, the LEE-BED project will provide the infrastructure necessary for the rapid development and pilot production of nanomaterials, inks, adhesives, and composites as well as digitally-enabled pilot production lines.

CPI is one of 17 partners contributing to this EU-funded Horizon 2020 project, with each partner bringing unique skills and capabilities in terms of technology innovation. In particular, CPI’s electronics and formulation capabilities will provide the project with a range of expertise in inks, adhesives and composite formulation, as well as in printable device fabrication, flexible electronics and electronic system design.

Click here to read more 

CPI accelerate commercialisation of lightweight products

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

Milestone Year For NETPark Based Kromek

Milestone Year For NETPark Based Kromek

This was a milestone year for Kromek as the Group delivered on all of its objectives, including the key target of growing adjusted EBITDA.

For the full year, revenue increased by 23% to £14.5m (2017/18: £11.8m) and adjusted EBITDA grew fourfold to £2.0m (2017/18: £0.5m). In particular, the Group successfully delivered its largest second half of revenue in its history, which was in excess of £10m. This progress was based on Kromek continuing to execute on previously-signed agreements as well as winning new customers, new contracts and repeat orders across its target markets, with growth driven by increasing adoption of the Group’s next-generation molecular imaging single photon emission computed tomography (“SPECT”) products in medical imaging and the D3S family of products in nuclear detection.

It also reflects the increasing commercialisation of Kromek’s technology, with product sales accounting for 83% of total revenue (2017/18: 81%), representing growth in value of 25%. Kromek was also awarded one of its most significant contracts to date, expected to be worth a minimum of $58.1m over a seven-year period, to provide cadmium zinc telluride (“CZT”) detectors and associated advanced electronics to be used in state-of-the-art medical imaging systems.

Click here to read more

Dr Arnab Basu, CEO Kromek Plc

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

CPI Supports GlycoSeLect to Develop High Throughput Glycan Analysis Platform for Biotherapeutics

CPI Supports GlycoSeLect to Develop High Throughput Glycan Analysis Platform for Biotherapeutics

CPI has contributed its expertise in biotherapeutics to support an Innovate UK funded project focused on developing and integrating novel recombinant prokaryotic lectins (RPLs) into a biosensor-based platform. The platform will enable simplified, rapid, high throughput and cost-effective characterisation and monitoring of the glycosylation of biotherapeutic products.

The collaboration between CPI, GlycoSeLect UK Ltd, ForteBio-Molecular Devices and Allergan Biologics Ltd addressed the need for new analytical approaches to satisfy the growing biotherapeutics market. As medicines, biotherapeutics have been shown to be highly effective in the treatment of a multitude of diseases. With more than two-thirds of biotherapeutics existing in a glycosylated form, it is important that the glycan profile is monitored throughout product development and manufacture.

Characterising the glycan profile of the biotherapeutic is a key product quality attribute, and is important in delivering a safe and efficacious medicine to the patient. However, the development and manufacture of these potentially life-changing treatments carries a high risk of failure, is technically challenging and is expensive.

CPI, operating from its Darlington-based National Biologics Manufacturing Centre, used GlycoSeLect’s glycan recognition technology and ForteBio-Molecular Devices’ biosensor-based analytical platform technology to create a novel glycan analysis platform with the capability to reduce costs and accelerate product development pipelines.

The project developed an assay platform to define the glycosylation profiles of biotherapeutics, using ForteBio-Molecular Devices’ Octet instrument to detect interactions between GlycoSeLect’s RPLs and a range of biotherapeutic proteins, which were provided by Allergan Biologics.

The assay platform, validated by the consortium partners, established linearity of response and limits of detection, robustness, reproducibility, and specificity. It was also found to be effective on both purified and in-process biotherapeutic proteins and allowed for real-time analysis.

The results demonstrated that combining GlycoSeLect’s innovative RPLs with Bio-Layer Interferometry (BLI) based assay technology fulfilled the main objective of the project; to create a rapid, cost-effective analytical platform. This platform is available for use with high throughput process development and in process control (IPC) approaches to enable glycan characterisation of a biotherapeutic product throughout development and manufacturing phases.

Dr John Liddell, Chief Technologist, Centre for Process Innovation, said: “CPI is delighted to have worked with GlycoSeLect UK Ltd as well as the other project partners, ForteBio-Molecular Devices and Allergan Biologics Ltd on this project supporting the development of an innovative, novel approach to rapidly analyse glycan profiles of biotherapeutic proteins. The rapid, high throughput platform developed for the key quality attribute of glycosylation will help to streamline development and manufacture of biotherapeutic proteins contributing to lower costs and faster development of new medicines.”

Robert Dunne, CEO of GlycoSeLect UK Ltd, said: “GlycoSeLect’s team were pleased to collaborate with their fellow researchers at CPI, ForteBio-Molecular Devices and Allergan to deliver a successful Innovate UK funded project. Our RPL technology has been shown to be the core of a high throughput analytical platform for glycan analysis of biotherapeutic products. On behalf of GlycoSeLect I want to thank our colleagues from CPI, Allergan ForteBio-Molecular Devices and InnovateUK for their input”

CPI Supports GlycoSeLect to Develop High Throughput Glycan Analysis Platform for Biotherapeutics

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

Kromek awarded $58m medical imaging contract

Kromek awarded $58m medical imaging contract

Kromek (AIM: KMK), a worldwide supplier of detection technology focusing on the medical, security screening and nuclear markets, is pleased to announce that it has been awarded a new contract, by an existing OEM customer, expected to be worth a minimum of $58.1m over a seven-year period.

Under the terms of the contract, Kromek will supply Cadmium Zinc Telluride (CZT) detectors and associated advanced electronics to be used in state-of-the-art medical imaging systems. The Company’s technology provides higher resolution detection capabilities enabling better patient outcomes.

Kromek will deliver the contract over a seven-year period, commencing immediately, and will begin recognising revenue from the 2019/2020 fiscal year.

Arnab Basu, CEO of Kromek, commented: “We are delighted to have been awarded this multi-year contract from an existing OEM customer, which is one of the most significant that we have secured both from a strategic and monetary perspective. It is also the first major contract that will be delivered from our new facility in the US that has been purpose built as a world-class production site for medical imaging products. Building on the $80m of contracts won over the last three fiscal years, this award strengthens and solidifies our revenue visibility and demonstrates the increasing commercial traction of our CZT detectors in our key target markets of medical imaging and nuclear detection.”

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The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

European space backing for Evince’s revolutionary technology

European space backing for Evince’s revolutionary technology

AN INNOVATIVE technology company that could revolutionise the electronics market with its diamond-based electronics devices has won a €200k project with the European Space Agency (ESA) that could transform the way satellites are used in space.

Evince Technology, based at the North East Technology Park (NETPark) in Sedgefield, County Durham, is working on a nine-month ESA-backed project with Mars Space, a space engineering consultancy, on developing its technology to deliver electron sources for use within electric propulsion systems for the space and satellite sector.

Evince is developing a process whereby it can embed tens of thousands of nano-scale electron emitters in a diamond substrate that could act as an electron source to replace the thermionic, or heated source, currently used within the propulsion system. The work is being funded via the ESA’s General Support Technology Programme.

Dr Gareth Taylor, CEO of Evince, said: “The European Space Agency is a key enabling partner in getting our technology to market. Just changing one thing on a satellite, such as the propulsion system is a game changer but ESA recognises our technology could also be used in other areas, such as broadcast communications, lower power communications and for improved power management.

“This is a UK-based technology where this project is just the start and actually we could end up taking the world lead in it. People use the words ‘game changing’ a lot but our technology really does have the power to revolutionise 21st century electronics.”

Neil Wallace, ESA technical officer for the programme, said: “We’re very excited by the development and keen to see the first coupling tests in the ESTEC Electric Propulsion Laboratory with a functioning thruster.”

Evince has a small in-house engineering team coupled with an established and growing network of academic and industrial partnerships, and has offices and a lab at NETPark, which is run by Business Durham, the economic development organisation for County Durham, which works on behalf of Durham County Council.

Catherine Johns, innovation director at Business Durham, said: “It’s a very exciting time for Evince as its revolutionary technology could have vast impacts on many different markets. It’s fantastic to see them at the stage where they’re working on so many applications and getting the funding they deserve to scale their business up from their base at NETPark.”

Evince was founded in 2008, then re-structured in 2013 to focus on the development of its core technology to enable the manufacture of a range of synthetic diamond-based electronics devices. The company secured £750k of new investment in September 2016, and has since secured over £1.3m of additional funding from its existing network of private investors and via technology grants and industrial partnerships.

The company’s technology has the power to realise electronics using synthetic diamond – which is 1,000 times purer than the naturally occurring mineral. Low-cost synthetic diamond offers the potential to create devices that are up to 100 times faster than silicon, as well as being more energy efficient and to offer a unique dual ability to withstand very high voltages across thin layers of the material while conducting heat five times better than copper. Diamond is also inherently radiation hard and more able to operate in harsh environments with far less degradation over time, hence its appeal to the space industry.

In July this year, Evince began working with companies in Denmark and Germany on a £1.42m project to use its technology in industrial X-ray sources which could lead to the world’s first diamond-based X-ray tube systems.

Said Gareth: “The RADICLE X-Ray collaboration will use our diamond-based technology in two different parts of an X-ray system – in the electron source and high voltage generator for the X-ray tube system, and also within its associated power supply.

“Our aim is to license our technology to major industrial partners across multiple sectors so they can exploit our ‘unique practical approach’ to deliver a completely new class of electronics devices. And to help a broad range of industries benefit from the vastly superior thermal and electronic properties that only diamond can offer.”

Gareth Taylor of Evince Technology with a Diamond Electron Source in the company's laboratory at NETPark in Segefield, County Durham. Photograph: Stuart Boulton.

Follow NETPark On Social Media

Keep up to date with the latest NETPark news and events.

NETPark Logo

The North East Technology Park provides a dynamic and supportive environment to accelerate the growth of ambitious, innovative, high tech companies into global markets. NETPark encourages collaborative multidisciplinary links, driving innovation, enterprise and economic prosperity.
We provide companies with access to a focused and international community where talent flourishes, ideas are generated and businesses have the support and resources to compete with the best in the world.

NETPark North East Technology Park

NETPark, North East Technology Park,
Sedgefield, County Durham TS21 3FD

Call Us: (+44) 01740 625250
Email: enquiries@northeasttechnologypark.com
Web: northeasttechnologypark.com

CPI has developed a specialist offering to support SMEs looking to develop their printable electronics applications and our partnership with Business Durham has been instrumental in attracting several SMEs to locate here in the region.

Dr Jon Helliwell, - Director of Printable Electronics, CPI

Access to quality facilities was one of the main drivers for deciding to locate the business at the NETPark. We have been able to use this as a launch pad to link into support from CPI and world-class expertise from Durham University.

Steve Clements, - Managing Director, aXenic

The quality of the facilities at NETPark and the attitude of staff is first class. It has a really dynamic, innovative atmosphere.

Dr Neil Loxley, - Chief executive, IBEX

We initially came because of the printable electronics centre but access to a highly skilled semi conductor workforce in the North East has been a key factor in us staying and growing here, as well as the value for money office space and the access to funding.

Ken Williamson, - COO, PragmatIC Printing

It fits perfectly for us that we’re surrounded by like-minded companies at NETPark. There are a number of highly skilled people in the area who can help us grow our business. The facilities and services offered by NETPark are first class, they make office life simple and engaging.

Stuart Wilson, - CEO, Ascarii

The proximity to the universities and the infrastructure are very important factors. Ultimately having a presence in Europe is very valuable to us and we intend to stay at NETPark for many years to come.

Dr Arnab Basu, - CEO, Kromek